Иммунитет крупного рогатого скота: практический подход к иммунологии и вакцинологии

КЛЮЧЕВЫЕ МОМЕНТЫ

• Му молочных коров после родов часто наблюдается снижение некоторых ключевых иммунных функций,. в частности, способности нейтрофилов убивать бактерии и реакции Т-клеток и В-клеток на антигены. Это называется околородовой иммунной дисфункцией.

• Я Некоторые изменения функционирования иммунных клеток крови, вероятно, отражают миграцию 3penbix нейтрофилов и макрофагов в ткани, особенно в репродуктивный тракт, и быстрый приток некоторых незрелых, менее функциональных клеток из костного мозга.

• Е] He все коровы транзитной группы проявляют признаки изменения иммунной функции. Генетическая селекция, снижение температуры в период сухостоя, вакцинация и профилактика гипокальциемии являются надежными средствами ограничения восприимчивости к инфекции после отела.

• Е] Появляются фармацевтические и диетические иммуномодуляторы, способные модулировать транзитныйфункционированиепериод. врожденного иммунитета, чтобы помочь преодолеть иммунную дисфункцию в

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